Synthetic Nicotine vape juice is any e-liquid containing nicotine that isn’t derived from tobacco leaves but is instead synthesized in a laboratory. There are a number of patents describing some of the different methods that have been discovered for creating Synthetic Nicotine. The general process, however, involves combining substances that react chemically with each other to generate nicotine and then using a solvent to isolate the nicotine from the solution.

You then have an isolated nicotine – or nicotine salt – that you can add to e-liquid or any other type of nicotine product. Vape juice isn’t the only product that people are making with Synthetic Nicotine these days; you can also find tobacco-free nicotine in products such as nicotine pouches.

Although it is possible to extract nicotine from other plants – eggplant and tomato are two well-known sources – the nicotine concentration in those foods is so low that you’d need hundreds of pounds of material just to extract enough nicotine for one bottle of e-liquid.

You’d have to eat about 20 eggplants, in fact, just to get the same amount of nicotine in a cigarette. So, when you see an e-liquid that contains “tobacco-free nicotine,” you can safely assume that the nicotine is synthetic. There’s simply no natural source other than tobacco that’s rich enough in nicotine to be worth the effort.

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Synthetic NicotineSynthetic Nicotine is used for E-Liquid
Synthetic Nicotine vape juice is any e-liquid containing nicotine that isn’t derived from tobacco leaves but is instead synthesized in a laboratory. There are a number of patents describing some of the different methods that have been discovered for creating Synthetic Nicotine. The general process, however, involves combining substances...