The development of synthetic nicotine needs technical improvement
Nicotine is optically active and has two different optical isomers. Among them, only S Isomer nicotine has mental activity, can combine with human brain receptors, and can produce addictive effect after use. Most of nicotine in natural tobacco is S Isomer nicotine, and the target isomer cannot be specified in the early Synthetic Nicotine process. In order to obtain pure S Isomer Synthetic Nicotine, further complex separation and purification are needed.
Because of the complex process and high cost, the proportion of synthetic nicotine used in tobacco products in the early years was still very low. In recent years, with the improvement of the process, the cost of Synthetic Nicotine has been reduced, and manufacturers have specially publicized the “advantages” such as “being able to bypass PMTA for direct marketing”, “not containing harmful impurities in tobacco” and “safe and harmless”, more and more people use Synthetic Nicotine.
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