A preparation method of synthetic nicotine
The invention discloses a preparation method of Synthetic Nicotine, belonging to the technical field of chemical synthesis.
The synthesis method of racemic (±) (R, s) nicotine and natural optically active body () (s) nicotine provided by the invention adopts nicotinic acid ester, diethyl succinate or n-alkyl succinimide as initial raw materials, It can overcome many defects of the existing Synthetic Nicotine technology, such as large-scale production difficulties, high cost, etc. specifically, the initial raw materials used in the synthesis method of racemic (±) (R, s) nicotine and natural optically active (s) nicotine provided by the invention are easy to obtain, the preparation process is simple and the cost is low, The prepared nicotine does not contain any harmful tobacco compounds and is suitable for industrial large-scale production.
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